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Number and Nature

Using Physiological Models to Investigate the Pathophysiology of Sepsis and Shock

March 13, 2026February 25, 2024 by Number and Nature

Sepsis and shock are life-threatening conditions that require a deep understanding of their underlying mechanisms. Physiological models serve as essential…

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Modeling the Biomechanics of Lung Expansion and Contraction During Breathing

March 13, 2026February 25, 2024 by Number and Nature

The process of breathing is essential for life, involving complex biomechanics within the lungs. Understanding how the lungs expand and contract during…

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Understanding the Dynamics of Circadian Rhythms in Physiological Processes

March 13, 2026February 25, 2024 by Number and Nature

Circadian rhythms are natural, internal processes that regulate the sleep-wake cycle and repeat roughly every 24 hours. These rhythms influence various…

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Physiological Modeling of Erythropoiesis and Red Blood Cell Lifespan Regulation

March 13, 2026February 25, 2024 by Number and Nature

Understanding how the body produces and regulates red blood cells (RBCs) is crucial in physiology and medicine. Erythropoiesis, the process of RBC production…

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Simulating the Effects of Pharmacological Agents on Neural and Cardiovascular Systems

March 13, 2026February 25, 2024 by Number and Nature

Understanding how pharmacological agents affect the human body is crucial for developing effective treatments for various conditions. Simulating these effects…

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Modeling the Role of Mitochondrial Function in Cellular Energy Production and Disease

March 13, 2026February 25, 2024 by Number and Nature

Mitochondria are often called the “powerhouses” of the cell because of their critical role in producing energy. Understanding how mitochondria function helps…

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Using Data-driven Physiological Models to Predict Disease Progression in Alzheimer’s Disease

March 13, 2026February 25, 2024 by Number and Nature

Alzheimer’s disease is a progressive neurodegenerative disorder that affects millions worldwide. Predicting how the disease will progress in individual…

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Physiological Models of the Mechanisms Underlying Obesity and Metabolic Syndrome

March 13, 2026February 24, 2024 by Number and Nature

Obesity and metabolic syndrome are complex health conditions influenced by various physiological mechanisms. Understanding these mechanisms is crucial for…

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Modeling the Interaction Between the Immune System and Infectious Agents

March 13, 2026February 24, 2024 by Number and Nature

Understanding how the immune system interacts with infectious agents is crucial for developing effective treatments and vaccines. Scientists use mathematical…

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Simulating the Effects of Nutritional Supplements on Metabolic Pathways

March 13, 2026February 24, 2024 by Number and Nature

Understanding how nutritional supplements influence our body’s metabolic pathways is crucial for both researchers and health enthusiasts. Simulating these…

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